Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5970
Gene Symbol: RELA
RELA 		0.300 Biomarker phenotype CTD_human Involvement of HIF-1α-regulated miR-21, acting via the Akt/NF-κB pathway, in malignant transformation of HBE cells induced by cigarette smoke extract. 29501572 2018
Entrez Id: 100302203
Gene Symbol: MIR1271
MIR1271 		0.300 Biomarker phenotype CTD_human MicroRNA-1271 suppresses the proliferation and invasion of colorectal cancer cells by regulating metadherin/Wnt signaling. 29315995 2018
Entrez Id: 4751
Gene Symbol: NEK2
NEK2 		0.300 Biomarker phenotype CTD_human Deguelin inhibits epithelial-to-mesenchymal transition and metastasis of human non-small cell lung cancer cells by regulating NIMA-related kinase 2. 28509438 2017
Entrez Id: 3158
Gene Symbol: HMGCS2
HMGCS2 		0.300 Biomarker phenotype CTD_human HMGCS2 enhances invasion and metastasis via direct interaction with PPARα to activate Src signaling in colorectal cancer and oral cancer. 27816970 2017
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.300 Biomarker phenotype CTD_human Estrogen and ERα enhanced β-catenin degradation and suppressed its downstream target genes to block the metastatic function of HA22T hepatocellular carcinoma cells via modulating GSK-3β and β-TrCP expression. 26990689 2017
Entrez Id: 100126328
Gene Symbol: MIR940
MIR940 		0.300 Therapeutic phenotype CTD_human Exosomal miR-940 maintains SRC-mediated oncogenic activity in cancer cells: a possible role for exosomal disposal of tumor suppressor miRNAs. 28423620 2017
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.300 Therapeutic phenotype CTD_human Estrogen and ERα enhanced β-catenin degradation and suppressed its downstream target genes to block the metastatic function of HA22T hepatocellular carcinoma cells via modulating GSK-3β and β-TrCP expression. 26990689 2017
Entrez Id: 8091
Gene Symbol: HMGA2
HMGA2 		0.300 Biomarker phenotype CTD_human HMGA2 upregulation mediates Cd-induced migration and invasion in A549 cells and in lung tissues of mice. 28830677 2017
Entrez Id: 196
Gene Symbol: AHR
AHR 		0.300 Therapeutic phenotype CTD_human Cytoplasmic aryl hydrocarbon receptor regulates glycogen synthase kinase 3 beta, accelerates vimentin degradation, and suppresses epithelial-mesenchymal transition in non-small cell lung cancer cells. 27752740 2017
Entrez Id: 406947
Gene Symbol: MIR155
MIR155 		0.300 Biomarker phenotype CTD_human MIR155 Regulation of Ubiquilin1 and Ubiquilin2: Implications in Cellular Protection and Tumorigenesis. 28315615 2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.300 Biomarker phenotype CTD_human Estrogen and ERα enhanced β-catenin degradation and suppressed its downstream target genes to block the metastatic function of HA22T hepatocellular carcinoma cells via modulating GSK-3β and β-TrCP expression. 26990689 2017
Entrez Id: 406997
Gene Symbol: MIR215
MIR215 		0.300 Therapeutic phenotype CTD_human The long noncoding RNA PCAT-1 links the microRNA miR-215 to oncogene CRKL-mediated signaling in hepatocellular carcinoma. 28887306 2017
Entrez Id: 283120
Gene Symbol: H19
H19 		0.300 Biomarker phenotype CTD_human Long non-coding RNA H19 promotes the proliferation and invasion of breast cancer through upregulating DNMT1 expression by sponging miR-152. 28544374 2017
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2 		0.300 Biomarker phenotype CTD_human Transforming activity and therapeutic targeting of C-terminal-binding protein 2 in Apc-mutated neoplasia. 28414304 2017
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1 		0.300 Biomarker phenotype CTD_human Long non-coding RNA H19 promotes the proliferation and invasion of breast cancer through upregulating DNMT1 expression by sponging miR-152. 28544374 2017
Entrez Id: 4627
Gene Symbol: MYH9
MYH9 		0.300 Biomarker phenotype CTD_human Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma. 28650484 2017
Entrez Id: 4660
Gene Symbol: PPP1R12B
PPP1R12B 		0.300 Biomarker phenotype CTD_human Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma. 28650484 2017
Entrez Id: 7159
Gene Symbol: TP53BP2
TP53BP2 		0.300 Biomarker phenotype CTD_human Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma. 28650484 2017
Entrez Id: 406933
Gene Symbol: MIR141
MIR141 		0.300 Therapeutic phenotype CTD_human Trans-nonachlor decreases miR-141-3p levels in human melanocytes in vitro promoting melanoma cell characteristics and shows a multigenerational impact on miR-8 levels in Drosophila. 27616325 2016
Entrez Id: 8518
Gene Symbol: ELP1
ELP1 		0.300 Biomarker phenotype CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016
Entrez Id: 91801
Gene Symbol: ALKBH8
ALKBH8 		0.300 Biomarker phenotype CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		0.300 Therapeutic phenotype CTD_human Elevated IL-1β expression induces invasiveness of triple negative breast cancer cells and is suppressed by zerumbone. 27567548 2016
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.300 Biomarker phenotype CTD_human Transcription factor activity of estrogen receptor α activation upon nonylphenol or bisphenol A treatment enhances the in vitro proliferation, invasion, and migration of neuroblastoma cells. 27366082 2016
Entrez Id: 7913
Gene Symbol: DEK
DEK 		0.300 Biomarker phenotype CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016
Entrez Id: 442911
Gene Symbol: MIR346
MIR346 		0.300 Biomarker phenotype CTD_human miR-346 promotes migration and invasion of nasopharyngeal carcinoma cells via targeting BRMS1. 27501413 2016